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Effects of Korean
Ginseng
On
Hepatopathy
Ginseng extracts have thr function of
stimulation biosynthesis of RNA, serum protain and
bone-marrow DNA.
Through serological
experiments, it was observed that a commonly used
hepatitis remedy supplemented with ginseng promoted
the recovery of B-type viral hapatitis, toxic and
drug induced hepatitis.
It was reported
that ginseng extracts reduced induction of alcoholic
anesthesia and maintenance and shortened recovery
time.
Clinical
Effect on Diabetes Mellitus
It was reported that ginseng
saponin components were effective in the induction
of hyperglycaemia by adrenalin.
It was revealed that ginseng was effective in the relief of general
subjective symptom and lowered the blood sugar level.
It was reported that using ginseng supplemented with insulin could reduce
the required insulin dosage.
On
Cancer
It was reported that fat-soluble components of ginseng inhibited the growth
of three types of cancer cells (Leukemic cells L5178Y, Hella cells, and Sarcoma
180 cells) in vivo and in vitro.
Ginseng inhibited subjectively the growth of cancer cells only and destroyed
cancer tissues.
Saponin was orally administered for 30 days at dose of 200 mg/day to breast
cancer patients(54)have high fever caused by overdose radiation. As the result,
the high fever was cleared, appetite improved, and leucocyte count and hemogram
normalized.
As a result of dressing 8g of ointment daily for 90days made from saponin
only to adbomina wound of the patient carried metastasis into cancerous
peritonitis and skin cancer caused by stomach cancer, it had not been develop
did not be shown process of cancer metastasis.
On
Atherosclerosis & Hypertention
It was observed the preventive effect of ginseng saponin against aortic
atheroma formation caused by hyperchoiesterolemia ginseng saponin might
stimulate the enzymes relating to the metabolism of lipids, particulary
choleterol.
It was reported that ginseng saponin stimulated the activity of enzymes
relating to the metabolism of lipid, and reduced the cholesterol level in blood.
Ginseng sponin has preventive effect against the formation of aortic
atheroma. It was reported that the active components of ginseng enhanced
cholesterol turnover and thus improved the hyperlipidemia, which is the major
detrimental factor of arteriosclerosis.
The administration of ginseng principles reduced the total cholesterol and
triglyceride level in blood and accelerated the depletion of serum colesterol.
Ginseng components also accelerated the excretion of cholesterol metabolites
and bile acids in faces.
Anti-fatigue
Effects
It was reported that the anti-fatique effect of ginseng extracts which might
arise from their inhibitory action on utilization of endogenous glycogen in
white muscle and lipid oxidation caused during continuous exerc-ise.
A total of 11 elderymen receiving ginseng extract were subjected to
exercise. Ginseng exerted an adaptoge-nic effect during exercise, and shortened
the heart rate recovery time.
The anti-fatique effect of ginseng was demonstrated through performance
studies dose on radio oporators and on nurses and swimmers by Yamada.
On
the Antistress
It was reported that ginseng that saponin exerted its effect on the
hypothalamohypo-physical system, thus stimulating the secretion of ACTH, which
it turn acted on the adrenal cortex to produce cyclic AMP. Then, the cyclic AMP
induced synthesis and secretion of corticosteroid, giving rise to an increase in
PLA-sma cortisone concenturation.
Its effects was confirmed, after administration of ginseng saponin to the
mouse through determination the concenturation of plasma ACTH by radio
immuno-assay and competitive protein binding method.
Nurses(both sexes)suffering from night duty were given ginseng powder on a
double blind, randomized, basis, and their blood was analyzed for several
metabolites and bomonal parameters. Ginseng corrected the blood sugar level
raised by stress.
Cardiotonic
Effects Cardiac hypertrophy was induced by artificial surgery in rabbits, thus as
the result of investigation effects between receiving ginseng group and control
group, it was more evident in rabbits receiving ginseng.
Cardiac hypertrophy was significantly prevented in test animals receiving
ginseng for 6 weeks before and after the operation.
This finding was attributed to and increaced Ca++uptake in the
cardiac sarcoplasmic reticulum and cellular membranes.
Tonic
Effects Fraction 4, isolated from ginseng extract, stimulated in vivo synthesis of
DNA and protein in testis.
Ginsenoside-triol(0.23g/day)was orally administrated to the 120
gynecologically-laparotomized patiens. As the result, the evident effects of
recovery were confirmed on various clinical symptoms.
The extent of elevation of the serum cholesterol level was significantly
lower in patients receiving ginseng, and the total serum protein level was more
significantly elevated in the finseng-treated group than in the control.
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